Age Related Macular Degeneration
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The University of Manchester, UK have been
investigating the role of the Macular Pigment and
its relation to AMD for many years. It is
suspected that a low level of macular pigment
increases the chance of suffering Macular
Degeneration in later life therefore some easy
method of assessing levels of macular pigment in an
individual, and hence their risk, is well
Based on their free view Portable Spectral Sensitivity Instrument, FOSSE, ( Perception 19, 359, 1990) they developed a simple technique to assess macular pigment density.
Further research has led to the development of a completely new instrument designed specifically to measure levels of macular pigment in the eye and eliminate the major problems encountered with conventional HFP techniques. For more detailed information have a look at the article in the Optician, Jan 2008. This article not only describes the MPS II basics but shows just how accurate and repeatable the data are. In this case an at risk subject with very low MPOD virtually doubled his levels by taking a supplement.
It is a compact low cost instrument, which is very easy to use particularly for the patient. It can be used for serious research and large scale clinical trials as well as more widespread use in Optometric Practice and Pharmaceutical Outlets where it requires minimal operator intervention and many subjects are able to carry out the test totally unaided in only a few minutes.
recent research study Patients, with early stage
ARMD in only one eye, together with age-matched
none-affected subjects, were given a lutein
supplement, which is known to be a vital element in
supporting the macular pigment. The findings
indicated that all reacted positively, and macular
pigment density increased. Some individuals reacted
quickly whilst others seemed to take up to six
months before the macular pigment density increased.
recent follow up major study preliminary results
show that subjects with early stage ARMD who took a
lutein supplement not only showed improvements in
their vision but also progression of macular
degeneration was significantly slowed.