Age Related Macular Degeneration

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Recent Research in Manchester relevant to Macular Degeneration and Dark Adaptation
Tahir, H. J., Rodrigo-Diaz, E., Parry, N. R., Kelly, J. M., Carden, D., & Murray, I. J. (2016). Slowed dark adaptation in older eyes; Effect of location. Experimental Eye Research.

Tian, Y., Kijlstra, A., Veen, R.L., Makridaki, M., Murray, I.J. and Berendschot, T.T., 2015. Lutein supplementation leads to decreased soluble complement membrane attack complex sC5b‐9 plasma levels. Acta ophthalmologica, 93(2), pp.141-145.

Tahir, H.J., Cerio, E., Parry, N.R., Kelly, J.M., Carden, D., Aslam, T.M. and Murray, I.J., 2015. Novel dual arc stimulus aids sensitive detection of early AMD. Investigative Ophthalmology & Visual Science, 56(7), pp.2617-2617.

de Cerio, E.R.D., Kelly, J.M., Carden, D. and Murray, I.J., 2015. The benefits of a Red Background when measuring Dark Adaptation. Investigative Ophthalmology & Visual Science, 56(7), pp.4312-4312.

E RODRIGO, HJ TAHIR, NRA PARRY, JMF KELLY, T ASLAM, D CARDEN, IJ MURRAY. (2014). A novel technique for measuring dark adaptation using a dual stimulus method: Effects of aging and AMD on dark adaptation. 92, eScholarID:231893 | DOI:10.1111/j.1755-3768.2014.T010.x

Patryas, L., Parry, N., Carden, D., Aslam, T. & Murray, I (2014). The association between dark adaptation and macular pigment optical density in healthy subjects. Graefe's Archive for Clinical and Experimental Ophthalmology, 1-7. eScholarID:219658

Patryas, Laura and Parry, Neil RA and Carden, David and Baker, Daniel H and Kelly, Jeremiah MF and Aslam, Tariq and Murray, Ian J. (2013). Assessment of age changes and repeatability for computer-based rod dark adaptation. Graefe's Archive for Clinical and Experimental Ophthalmology, 1-7. eScholarID:194239

Murray, I., Makridaki, M., van der Veen, R., Carden, D., Parry, N. & Berendschot, T (2013). Lutein Supplementation over a One-Year Period in Early AMD Might Have a Mild Beneficial Effect on Visual Acuity: The CLEAR Study. Investigative Ophthalmology & Visual Science, 54(3), 1781-1788. eScholarID:219647 | DOI:10.1167/iovs.12-10715

Murray, I., Hassanali, B. & Carden, D (2013). Macular pigment in ophthalmic practice; a survey.Graefes Archive for Clinical and Experimental Ophthalmology, 251(10), 2355-2362. eScholarID:219644 | DOI:10.1007/s00417-013-2430-4

Tian, Y., Kijlstra, A., Van der Veen, R., Makridaki, M., Murray, I. & Berendschot, T (2013). The Effect of Lutein Supplementation on Blood Plasma Levels of Complement Factor D, C5a and C3d. Plos One, 8(8), eScholarID:219646 | DOI:UNSP e73387 10.1371/journal.pone.0073387

Laura Patryas. (2013). Dark adaptation: methods and clinical significance. Presented at Manchester Optometry Meeting. Postgraduate Medical Centre, Manchester Royal Infirmary. eScholarID:225958

L Patryas, J Cher, IYF Leung, K Neelam, M Makridaki, D Carden, TTJM Berendschot, RLP van der Veen & IJ Murray. (2013). The MPS II; comparison with the Macular Pigment Reflectometer and the Macular Densitometer. Presented at Macular Carotenoid Conference. Cambridge. eScholarID:225960

Laura Patryas. (2011). Potential role of macular pigment in preserving rod-dominated dark adaptation in the older eye. Presented at British Congress of Optometry and Vision Science. Aston University, Birmingham. eScholarID:131338

Laura Patryas, Neil R.A. Parry, Dave Carden, Tariq Aslam, Ian J. Murray. (2011). Rod sensitivity recovery in the older eye. Presented at European Conference on Visual Perception. Toulouse, France. eScholarID:131337

Murray IJ, Carden, D and Makridaki M. (2010). The repeatability of the MPS 9000 macular pigment screener. British Journal of Ophthalmology. In Press, eScholarID:108361

Rob L. P. van der Veen, Tos T. J. M. Berendschot, Maria Makridaki, Fred Hendrikse, David Carden, Ian J. Murray
Correspondence between retinal reflectometry and a flicker-based technique in the measurement of macular pigment spatial profiles. Journal of Biomedical Optics 14(6), 064046 (November/December 2009)

Makridaki M, Carden D, Murray IJ. (2009). Macular pigment measurement in clinics: controlling the effect of the ageing media. Ophthalmic and Physiological Optics, 29(3), 338-344.

van der Veen, Rob L. P.; Berendschot, Tos T. J. M.; Hendrikse, Fred; Carden, David; Makridaki, Maria; Murray, Ian J (2009). A new desktop instrument for measuring macular pigment optical density based on a novel technique for setting flicker thresholds. Ophthalmic & Physiological Optics. 29(2):127-137, March 2009.

IJ Murray, D Carden (2008).  The Mpod - a new instrument for measuring macular pigment
The Optician, January 2008.

C J Bassi,  B Sobieralski, K Boland, B Brunig, B Borello, D Carden, IJ Murray. (2006). Rapid Measurement of Macular Pigment in the Clinic: Evaluation of the QuantifEye. American Academy of Optometry, Academy 2006 Denver.

Koh H-H, IJ Murray, D. Nolan, D. Carden, J. Feather and S Beatty. (2004). Plasma and Macular Responses to Lutein Supplement in Subjects With and Without Age-Related Maculopathy : a Pilot Study.  Exp Eye Res. 2004 Jul;79(1):21-7. 

Murray, IJ. ARM, macular pigment and lutein.  The Optician, (February 2003)

Declan J. McKeefry, Neil R. A. Parry, and Ian J. Murray. Simple Reaction Times in Color Space: The Influence of Chromaticity, Contrast, and Cone Opponency. Invest. Ophthalmol. Vis. Sci., (May 2003); 44: 2267 - 2276.

Sharanjeet-Kaur, O’Donoghue E.  and Murray I.J. (2003) Spectral Sensitivity in eyes with macular holes and their fellow eyes. Clin. Exp Optometry, 86;6, 385-389.

H-H Koh, IJ Murray, JW Feather, D Carden and DJ Nolan  (2002). Macular Pigment Optical Density in Early, Age-Related Maculopathy (ARM); Comparisons With Normals and Effects of a Lutein Supplement. Invest Ophthalmol Vis Sci 2002;43:

Beatty S., Murray I.J.,  Henson D.B., Koh H.H.,  Carden D., Boulton M.E. (2001) Macular Pigment and Risk for Age-Related Macular Degeneration in a Northern European Population.  Investigative Ophthalmology and Visual Science. 42, 2 439-446 

Beatty S., Koh H-H, Carden D., and Murray I.J. (2000) Macular pigment optical density measurement; a novel compact instrument. Ophthalmic and Physiological Optics. 20,2 105-111.

Beatty S, Koh H, Phil M, Henson D, Boulton M. (2000) The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol.  Sep-Oct;45(2):115-34. Review. 

Beatty  S.,  Boulton M., Henson D., Koh H-H and Murray I.J. (1999) Macular pigment and age related macular degeneration. Brit Journal of Ophthalmology 83, 7 pp 867-877

Sharanjeet-Kaur, J. J. Kulikowski, D. Carden (1998).  Isolation of chromatic and achromatic mechanisms: A new approach.  Ophthalmic and Physiological Optics 18 (1), 49–56.

John Dalton's Colour Vision Legacy.  Eds: CM Dickinson, IJ Murray, D Carden.  Taylor & Francis, London.  (1997).

Carden D, Simpson J, Parry NRA, and Murray IJ. A portable fibre optic device for measuring spectral sensitivities. Perception 19, 359, (1990).

Luminance and opponent-color contributions to visual detection and adaptation and to temporal and spatial integration
P. E. King-Smith and D. Carden.  JOSA, Vol. 66, Issue 7, pp. 709-717  (1976)